Everything You Need to Know About the Weight Gain That Can Occur While Taking Antidepressants.

Gaining weight is one of the potential adverse effects of taking numerous antidepressant medications. The following list of antidepressants may be more likely to induce weight gain while you are taking them for treatment of depression, despite the fact that each individual reacts differently to antidepressant medication. In here, we are going to explorer about, what kind of antidepressants that cause weight gain?

antidepressants for weight gain - use medications

1.Tricyclic Antidepressants.

Gaining weight is a possible side effect of using tricyclic antidepressants, often known as cyclic antidepressants or TCAs. Among these medications are:

  • Amitriptyline (Elavil).
  • Amoxapine.
  • Desipramine (Norpramin).
  • Doxepin (Adapin).
  • Imipramine (Tofranil-PM).
  • Nortriptyline (Pamelor).
  • Protriptyline (Vivactil).
  • Trimipramine (Surmontil).

TCAs were among the first medications that were authorized for use as a treatment for depression. Because newer medicines generate fewer negative effects, they are not recommended nearly as often as they formerly were.

According to a research that was conducted in 1984, one of the most common reasons patients terminated therapy with these kinds of antidepressants was because it caused them to gain weight.

Despite the fact that they have unpleasant side effects, tricyclic antidepressants (TCAs) can be helpful for those who do not react favorably to other types of antidepressant medicines.

2. Some Monoamine Oxidase Inhibitors (Maois).

MAOIs, which stands for monoamine oxidase inhibitors, were the first type of antidepressant to be discovered and created. The following are examples of MAOIs that promote weight gain:

  • Phenelzine (Nardil).
  • Isocarboxazid (Marplan).
  • Tranylcypromine (Parnate).

When other antidepressants don’t work owing to particular side effects or safety issues, MAOIs are the type of medication that is most commonly prescribed by doctors. A review that was done in 1988 found that among the three MAOIs that were mentioned before, phenelzine was the one that was most likely to cause weight gain. Source You Can Rely On.

On the other hand, a more recent formulation of an MAOI called selegiline (Emsam) has been proven to result in weight reduction while being treated for the condition. The drug known as Emsam is one that is administered transdermally through the use of a patch on the skin.

3. The Usage Of Particular Selective Serotonin Reuptake Inhibitors Over An Extended Period Of Time (Ssris).

The SSRIs are the most used type of antidepressant medication provided to patients. When used for an extended period of time, the following SSRIs may lead to weight gain:

  • Paroxetine (Paxil, Pexeva, Brisdelle).
  • Sertraline (Zoloft).
  • Fluoxetine (Prozac).
  • Citalopram (Celexa).

Long-term use of SSRIs is often connected to weight increase, despite the fact that initial usage of several SSRIs are associated with decreased body weight. Treatment that continues for more than half a year is regarded to be of the long-term usage variety.

The risk of weight gain is greatest with paroxetine, both with short-term and long-term treatment, making it the most prominent side effect of the SSRIs described above.

4. Some Atypical Antidepressants.

A noradrenergic antagonist, also known by its brand name Remeron, mirtazapine is classified as an unusual kind of antidepressant. It has been demonstrated on several occasions (Reliable Source) that the medication is more likely than other medications to result in increased hunger and weight gain.

In comparison to TCAs, mirtazapine is associated with a lower risk of leading to weight gain in patients.

Additionally, in comparison to other antidepressants, it does not cause nearly as many additional unpleasant side effects. On the other hand, it may result in:

  • Nausea.
  • Vomiting.
  • Dysfunctions of the sexual organs

Medications For Depression That Are Less Likely To Cause Users To Gain Weight.

antidepressants for weight gain - check dose of medication

There is some evidence that suggests that using some other antidepressants may result in reduced weight gain. The following are examples of antidepressants:

  • Escitalopram (Lexapro, Cipralex), an SSRI.
  • Long-term usage of the SNRI duloxetine (Cymbalta), also known as a serotonin-norepinephrine reuptake inhibitor (SNRI), may result in a little increase in body fat.
  • Source You Can Rely On.
  • An atypical antidepressant known as bupropion (brand names include Wellbutrin, Forfivo, and Aplenzin).
  • Nefazodone (Serzone), a serotonin antagonist and reuptake inhibitor.
  • Venlafaxine (brand name: Effexor) and venlafaxine extended release (trade name: Effexor XR), both of which are classified as SNRIs.
  • Desvenlafaxine (Pristiq), an SNRI.
  • Levomilnacipran (Fetzima), an SNRI.
  • Vilazodone (Viibryd), a serotonergic antidepressant.
  • An atypical antidepressant known as vortioxetine (trade name Trintellix).
  • Selegiline, also known as Emsam, is a relatively new MAOI that is administered topically and has the potential to have less adverse effects than MAOIs that are used orally.

When taken for a period of less than six months, the following SSRIs have been shown to have a lower risk of leading to weight gain:

  • Sertraline (Zoloft).
  • Fluoxetine (Prozac) (Prozac).
  • Citalopram (Celexa).

The Final Thought

People who use antidepressants do not always all put on weight. There will be some people who are successful in their weight loss.

The majority of depressed persons should not let their concerns about putting on weight affect their choice of antidepressant, according to the recommendations of experts. When selecting an antidepressant, you should also keep in mind that there are a number of additional potential side effects and variables.

Even if you do manage to put on some weight while taking an antidepressant, it is possible that the medication is not the primary reason for the weight gain. When you take an antidepressant, for instance, your mood may improve, which may cause an increase in your hunger, which may result in weight gain.

Even if you see a slight increase in your weight, you shouldn’t immediately stop taking your medication. You and your doctor will need to conduct some research to identify an antidepressant that is effective in treating the symptoms of your depression but does not cause any undesirable side effects. This could require a little bit of your time and patience.

Meat a doctor for antidepressants

While you are receiving treatment for depression with an antidepressant, your primary care physician can also provide you with some pointers to help you avoid gaining weight.


What antidepressants help with weight?

There are three antidepressant drugs that have been linked to weight reduction, despite the fact that the majority of antidepressant medications are more typically related with weight gain: Bupropion (Wellbutrin) (Wellbutrin) Fluoxetine (Prozac) Duloxetine (Cymbalta)

Can antidepressants help with weight gain?

Although some patients do experience weight gain after beginning treatment with an antidepressant, this is not usually due to the medication itself. During treatment with antidepressants, weight gain may be caused by a number of different mechanisms. For instance, depression can lead to weight gain due to behaviors such as overeating or decreased activity levels.

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.